Synthetic peptides used for identification of SOX-CAL binding site

Synthetic peptide from LifeTein were used to identify the SOX-CAL binding site. Long peptides including helix 1 of the HMG domain were synthesized by LifeTein. The peptides were used to examine the interaction of CaM with the CaM-binding domain of SOX9 (SOX-CAL). The researcher found two binding sites: the well-know high-affinity CaM binding site, and a lower-affinity binding site.

Please click here for the article: http://onlinelibrary.wiley.com/doi/10.1002/cbic.201402414/abstract

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