Dissolving a hydrophobic peptide could be tricky. LifeTein's website offers free information for researchers on how to dissolve peptides in polar organic solvents such as DMSO or ethanol. The website on how to handle and dissolve peptides was cited in Extremophiles. Lifetein's guideline is helpful for researchers to understand the basic procedure on how to dissolve peptides using the best solvent without sacrifice the protein activity at non-aqueous environments.
The reference was published on Extremophiles: DOI: 10.1007/s00792-014-0683-4
Effect of organic solvents on the structure and activity of moderately halophilic Bacillus sp. EMB9 protease
R Sinha, SK Khare - Extremophiles
Read more on how to handle and dissolve peptides: http://www.lifetein.com/handling_and_storage_of_synthetic_peptides.html
LifeTein, located in Somerset, New Jersey, was founded in 2008 with a simple vision: understanding life one protein at a time. This philosophy has formed the foundation of every peptide, antibody, protein, antibody, and chemical project that we have completed for our customers in the academic, biotechnology, agricultural, government institutions and pharmaceutical fields.
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